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Sleep problems: can AI and Digital Twin assist? | by Tatyana Kanzaveli | Jan, 2023

January 22, 2023
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In response to the Nationwide Sleep Basis, it’s estimated that fifty–70 million adults in the US have a sleep problem.

Sleep problems can have severe implications on an individual’s bodily and psychological well being. A few of the potential results embrace:

Elevated danger of accidents and accidents, attributable to drowsy driving, falling asleep on the wheel, or different lapses in attentionChronic fatigue and exhaustion, which may result in decreased productiveness and general high quality of lifeIncreased danger of growing power well being circumstances, resembling weight problems, diabetes, hypertension, and coronary heart diseaseIncreased danger of melancholy and anxietyIncreased danger of stroke and heart problems -Impression on cognitive operate, reminiscence, and skill to be taught.

Diagnosing sleep problems may be difficult for a number of causes:

Many individuals with sleep problems aren’t conscious they’ve one, and will not search medical consideration till the dysfunction has triggered vital issues of their life.Sleep problems may be brought on by a variety of things, together with medical circumstances, medicines, way of life habits, and psychological points. This makes it troublesome to pinpoint a selected trigger.Some sleep problems, resembling sleep apnea and insomnia, may be troublesome to diagnose as a result of they don’t all the time produce apparent signs.Many sleep problems aren’t seen throughout regular daytime actions, and require specialised testing, resembling polysomnography, in a sleep lab to be recognized.

Sleep drugs is a subspecialty of a number of medical fields, together with pulmonology, neurology, psychiatry, and otolaryngology. Physicians who focus on sleep drugs have accomplished extra coaching and schooling within the analysis and therapy of sleep problems.

Entry to sleep specialists and sleep problem therapy may be restricted in underserved communities. Elements resembling lack of insurance coverage protection, restricted availability of healthcare suppliers in sure areas, and transportation challenges could make it troublesome for individuals in these communities to entry the care they want. Moreover, cultural, linguistic, and financial boundaries may also play a job in stopping people from searching for and receiving care. In response to the American Academy of Sleep Medication, underserved populations, together with racial and ethnic minorities, low-income people, and rural residents are disproportionately affected by sleep problems and have much less entry to acceptable care.

When sufferers aren’t recognized well timed with their sleep problems, a number of destructive results can happen:

Worsening of signs: If a sleep problem just isn’t recognized and handled, signs might worsen over time. For instance, if a affected person has sleep apnea, their sleep disruptions and low oxygen ranges can result in hypertension, coronary heart illness, or stroke.Diminished high quality of life: If a sleep problem just isn’t recognized and handled, it could have a destructive impression on a affected person’s high quality of life. Signs resembling insomnia, daytime sleepiness, and fatigue could make it troublesome for sufferers to operate of their day by day lives.Elevated healthcare prices: If a sleep problem just isn’t recognized and handled, it could result in extra frequent and longer hospital stays, in addition to extra medical procedures and coverings.Elevated danger of accidents: If a sleep problem just isn’t recognized and handled, it could enhance the chance of accidents, resembling automotive accidents or falls.Different well being issues: If a sleep problem just isn’t recognized and handled, it could result in different well being issues, resembling melancholy, anxiousness, and cognitive impairment.

Built-in care groups play an necessary position in treating sufferers with sleep problems. An built-in care group is made up of healthcare professionals from totally different disciplines who work collectively to offer coordinated, patient-centered care. Within the context of sleep problems, an built-in care group might embrace:

Sleep specialists: resembling pulmonologists, neurologists, or otolaryngologists, have experience within the analysis and therapy of sleep problems.Major care physicians: who can refer sufferers to specialists and supply ongoing care and monitoring of sleep problems.Nurses: who can present schooling and help to sufferers with sleep problems.Psychologists or behavioral therapists: who can present cognitive behavioral remedy (CBT) for insomnia, which is an evidence-based therapy for insomnia.Technologists: who can present sleep research and different diagnostic assessments.Dietitians or nutritionists: who can present schooling and suggestions on diet and way of life modifications that may enhance sleep.Pharmacists: who can present schooling on medicines used to deal with sleep problems, and monitor for potential drug interactions.

An built-in care group may also help to make sure that sufferers with sleep problems obtain acceptable care and therapy. They will additionally assist to enhance affected person outcomes by offering coordinated, patient-centered care that addresses the bodily, emotional, and social points of sleep problems.

The perfect care group composition to deal with sufferers with sleep problems will depend upon the particular wants of the affected person and the kind of sleep problem they’ve. Nevertheless, a typical care group for sleep problems might embrace the next members:

Sleep specialist: A sleep specialist, resembling a pulmonologist, neurologist, or otolaryngologist, who has experience within the analysis and therapy of sleep problems.Major care doctor: A major care doctor who can refer sufferers to specialists and supply ongoing care and monitoring of sleep problems.Nurse: A nurse who can present schooling and help to sufferers with sleep problems.A psychologist or behavioral therapist: A psychologist or behavioral therapist who can present cognitive behavioral remedy (CBT) for insomnia, which is an evidence-based therapy for insomnia.Technologist: A technologist who can present sleep research and different diagnostic assessments.Dietitian or nutritionist: A dietitian or nutritionist who can present schooling and suggestions on diet and way of life modifications that may enhance sleep.Pharmacist: A pharmacist who can present schooling on medicines used to deal with sleep problems, and monitor for potential drug interactions.

Examples of built-in care therapy plans for sufferers with sleep problems embrace:

Behavioral therapy-based therapy plan: This plan might embrace cognitive behavioral remedy (CBT) for insomnia, which is an evidence-based therapy for insomnia. This remedy could also be supplied by a therapist or psychologist and will embrace methods resembling sleep restriction, stimulus management, and leisure coaching.Treatment-based therapy plan: This plan might embrace using remedy to deal with particular sleep problems, resembling sleep apnea, insomnia, and stressed legs syndrome. Medicines might embrace sedative-hypnotics, melatonin receptor agonists, or different medicines that focus on the particular sleep problem.Way of life changes-based therapy plan: This plan might embrace suggestions for modifications in weight loss program, train, and sleep hygiene, in addition to using mild remedy or different non-pharmacological approaches to enhance sleep.Medical device-based therapy plan: This plan might embrace using medical units resembling steady constructive airway strain (CPAP) machines, actigraphy units, or transportable sleep monitoring units.Mixture therapy plan: This plan might embrace a mixture of various kinds of therapy, resembling a mixture of behavioral remedy, remedy, and way of life modifications, tailor-made to the particular wants of the affected person.

PatientSphere by Open Well being Community is a digital platform that may assist with managing built-in care plans for sufferers with sleep problems in a number of methods:

Offering a centralized location for affected person info: PatientSphere can be utilized to retailer and share affected person info, resembling sleep research outcomes, therapy plans, and affected person progress, among the many totally different members of the care group.Bettering communication and coordination: PatientSphere can be utilized to facilitate communication and coordination among the many totally different members of the care group, resembling sleep specialists, major care physicians, and behavioral therapists.Customized therapy plans: PatientSphere can be utilized to create customized therapy plans for sufferers with sleep problems. This will embrace a mixture of various kinds of therapy, resembling a mixture of behavioral remedy, remedy, and way of life modifications, tailor-made to the particular wants of the affected person.Monitoring and monitoring affected person progress: PatientSphere can be utilized to watch and monitor affected person progress over time. This will embrace monitoring sleep patterns, remedy utilization, and different related info, which can be utilized to make changes to the therapy plan as wanted.Distant monitoring and telemedicine: PatientSphere may also facilitate distant monitoring and telemedicine, permitting sufferers to entry care and therapy remotely, which may be useful for sufferers who’ve issue accessing in-person remedy, and supply a handy and cost-effective method for sufferers to handle their sleep problems.

There are a number of new improvements and areas of analysis associated to sleep problems have emerged lately. A few of these embrace:

Wearable know-how: Wearable units resembling smartwatches and health trackers can monitor sleep patterns, detect sleep apnea, and monitor different sleep-related knowledge resembling coronary heart price, motion, and oxygen ranges.Digital therapeutics: Software program-based interventions which can be clinically validated and used to deal with or handle medical circumstances, resembling insomnia.Synthetic Intelligence and Machine Studying: AI and ML applied sciences are getting used to investigate affected person knowledge, predict the chance of growing sleep problems and make customized therapy suggestions.Digital Twin: Digital fashions of a bodily system, course of, or individual, that can be utilized to simulate and analyze real-world circumstances, resembling sleep patterns.Medical Units: there are new medical units have been developed resembling steady constructive airway strain (CPAP) units, Actigraphy, and transportable sleep monitoring units, that are used for the analysis and therapy of sleep problems.Non-Pharmacological Approaches: Research have been performed to discover the effectiveness of non-pharmacological approaches resembling mindfulness-based interventions, mild remedy, and bodily exercise in treating sleep problems.Analysis in sleep-related problems: There was a major enhance in analysis on sleep-related problems resembling narcolepsy, insomnia, sleep apnea, stressed legs syndrome, and different sleep-related problems to grasp the underlying causes, and develop new therapies.

Digital well being has the potential to play a major position in serving to sufferers with sleep problems. Digital well being applied sciences, resembling cellular apps, distant monitoring units, and digital therapeutics, can present a extra handy, accessible, and cost-effective method for sufferers to handle their sleep problems.

Some examples of digital well being applied sciences that can be utilized to assist sufferers with sleep problems embrace:

Cell apps: There are a selection of cellular apps accessible that may assist sufferers monitor their sleep patterns, set sleep objectives, and obtain customized sleep suggestions. Some apps additionally incorporate options resembling white noise mills, guided meditation, and sleep-promoting music to assist with insomnia.Distant monitoring units: Wearable units resembling smartwatches and health trackers can be utilized to trace sleep patterns, detect sleep apnea, and monitor different sleep-related knowledge resembling coronary heart price, motion, and oxygen ranges.Digital therapeutics: These are clinically validated software-based interventions which can be used to deal with or handle medical circumstances. Digital therapeutics can be utilized to offer cognitive behavioral remedy for insomnia (CBT-I) or different evidence-based therapies for sleep problems, remotely.Telemedicine: Telemedicine can be utilized to attach sufferers with sleep specialists for distant consultations, follow-up appointments, and monitoring of their sleep problem therapy.

There are a selection of cellular apps accessible that may assist sufferers with sleep problems monitor their sleep patterns, set sleep objectives, and obtain customized sleep suggestions. Some well-liked apps embrace Sleep Cycle, Sleep Time, and Sleep as Android, to call a couple of. These apps may be useful in offering info on sleep patterns and serving to customers determine potential points.

Some execs of utilizing cellular apps for sufferers with sleep problems embrace:

Comfort: Cell apps can be utilized at any time and from any location, making it straightforward for sufferers to trace their sleep patterns and set sleep objectives.Personalization: Many apps can present customized suggestions based mostly on a affected person’s sleep knowledge, which may also help to determine particular points and goal them extra successfully.Price-effective: Many sleep-tracking apps are free or low-cost, making them accessible to a variety of sufferers.Motivation: Some apps embrace options resembling progress monitoring, which may also help to encourage sufferers to make modifications that may enhance their sleep.

Some cons of utilizing cellular apps for sufferers with sleep problems embrace:

Knowledge accuracy: Apps depend on self-reported knowledge, which might not be totally correct.Lack of correct analysis or therapy plan: Many apps don’t present a correct analysis or therapy plan for sleep problems, and it’s endorsed to seek the advice of with a healthcare supplier for a correct analysis and therapy.Lack of clinically validated knowledge: Some apps might not be clinically validated, which means that the data supplied might not be scientifically correct or evidence-based.Consistency: Some customers might have bother utilizing the apps persistently, which may make it troublesome to trace patterns or see enchancment

Digital therapeutics (DTx) are clinically validated software-based interventions which can be used to deal with or handle medical circumstances. Some digital therapeutics which can be accessible for sufferers with sleep problems embrace:

CBT-I Coach: This app offers cognitive behavioral remedy for insomnia (CBT-I), which is an evidence-based therapy for insomnia. It consists of modules on sleep schooling, sleep diaries, leisure methods, and objective setting.Sleepio: This app offers a sleep enchancment program that’s based mostly on cognitive behavioral remedy for insomnia (CBT-I). It consists of modules on sleep schooling, sleep diaries, and customized sleep suggestions.SHUTi: This app offers cognitive behavioral remedy for insomnia (CBT-I) and consists of modules on sleep schooling, sleep diaries, and customized sleep suggestions.DreamMoods: This app offers sleep schooling, a sleep diary, and customized suggestions based mostly on dream evaluation.Re-timer: This app offers mild remedy, which is a therapy for insomnia and different sleep problems.

Digital therapeutics (DTx) may also help enhance the well being of sufferers with sleep problems in a number of methods:

They will present entry to evidence-based therapies: Digital therapeutics resembling CBT-I Coach, Sleepio, and SHUTi present cognitive behavioral remedy for insomnia (CBT-I), which is an evidence-based therapy for insomnia. This may also help sufferers enhance their sleep patterns, enhance the time they spend in mattress asleep, and scale back insomnia signs.They will present customized suggestions: Digital therapeutics can present customized suggestions based mostly on the affected person’s sleep patterns and different knowledge. This may also help sufferers determine particular points and goal them extra successfully.They will enhance adherence to therapy: Digital therapeutics can e used within the comfort of the affected person’s house and can be utilized at any time, which may enhance adherence to therapy. This may also help to make sure that sufferers obtain the suitable quantity of therapy and that therapy is simpler.They will scale back healthcare prices: Digital therapeutics is usually a less expensive different to in-person remedy, which may scale back healthcare prices for sufferers.They will enhance affected person engagement: Digital therapeutics may also help to extend affected person engagement by offering a extra interactive and customized expertise. This may also help to make sure that sufferers are extra concerned in their very own care and are extra motivated to make modifications that may enhance their sleep.

Digital therapeutics for sufferers with sleep problems have a number of potential cons:

Restricted effectiveness: Some digital therapeutics might not be as efficient as conventional therapies, resembling cognitive behavioral remedy (CBT) or remedy.Lack of regulation: There may be at the moment an absence of regulation for digital therapeutics, which implies that there could also be variations within the high quality and security of various merchandise.Restricted entry: Digital therapeutics might not be accessible to all sufferers, significantly these in underserved communities who might not have entry to smartphones or the web.Restricted human interplay: Some sufferers might desire face-to-face remedy slightly than digital remedy, as it could present them with extra personalization, emotional help, and a way of accountability.Privateness considerations: Some sufferers could also be hesitant to share their private info with digital therapeutics, attributable to considerations about knowledge privateness and safety.Restricted knowledge: There may be restricted knowledge on the long-term results of digital therapeutics, so it isn’t but clear how effectively they work over time.Restricted human oversight: Digital therapeutics might not present the identical degree of human oversight as conventional therapies, which may be necessary for sufferers with complicated medical circumstances.

Synthetic intelligence (AI) and machine studying (ML) applied sciences have the potential to be useful in treating sufferers with sleep problems in a number of methods:

Predictive modeling: AI and ML can be utilized to investigate affected person knowledge and predict which sufferers are on the highest danger of growing sleep problems. This may also help healthcare suppliers to determine sufferers who might have extra monitoring or therapy.Prognosis: AI and ML can be utilized to investigate affected person knowledge, together with sleep research outcomes, to assist diagnose sleep problems. Some AI algorithms have been developed to assist determine sleep apnea, which is a typical sleep problem.Therapy suggestions: AI and ML can be utilized to investigate affected person knowledge and make customized therapy suggestions. For instance, AI algorithms can analyze affected person knowledge to determine the best therapy for insomnia.Monitoring: AI and ML can be utilized to watch sufferers’ sleep patterns and supply alerts if there are any modifications which will point out a sleep problem.Telemedicine: AI and ML can be utilized to investigate affected person knowledge remotely, which may be useful in offering telemedicine providers for sufferers with sleep problems.

A digital twin is a digital mannequin of a bodily system, course of, or individual, that can be utilized to simulate and analyze real-world circumstances. Within the context of treating sufferers with sleep problems, a digital twin can be utilized to simulate a affected person’s sleep patterns and analyze their sleep knowledge. This may be useful in a number of methods:

Predictive modeling: A digital twin can be utilized to foretell a affected person’s danger of growing a sleep problem and supply customized therapy suggestions.Prognosis: A digital twin can be utilized to investigate a affected person’s sleep knowledge, together with sleep research outcomes, to assist diagnose sleep problems.Therapy planning: A digital twin can be utilized to simulate totally different therapy choices and predict their effectiveness for a selected affected person.Monitoring: A digital twin can be utilized to watch a affected person’s sleep patterns and supply alerts if there are any modifications which will point out a sleep problem.Customized suggestions: A digital twin can be utilized to offer customized suggestions for bettering sleep based mostly on a affected person’s particular sleep patterns and knowledge.Telemedicine: A digital twin can be utilized in telemedicine to offer distant consultations and follow-up appointments for sufferers with sleep problems.

The digital twin initiative by Open Well being Community and Miller College of Medication goals to create a digital mannequin of a affected person’s sleep patterns to assist diagnose and deal with sleep problems. By simulating a affected person’s sleep patterns and analyzing their sleep knowledge, the digital twin may also help determine particular points and goal them extra successfully. This will result in new therapy choices for sufferers with sleep problems.

The digital twin can be utilized to simulate totally different therapy choices and predict their effectiveness for a selected affected person. This may also help healthcare suppliers to determine the best therapy for a affected person’s sleep problem, and make customized therapy suggestions.

The digital twin can be used to watch a affected person’s sleep patterns and supply alerts if there are any modifications which will point out a sleep problem. This may also help to make sure that sufferers with sleep problems obtain acceptable care and therapy in a well timed method.

Moreover, the digital twin can be utilized in telemedicine to offer distant consultations and follow-up appointments for sufferers with sleep problems. This may be useful in offering entry to therapy for sufferers who might have issue accessing in-person remedy and offering a handy and cost-effective method for sufferers to handle their sleep problems.

In conclusion, AI and digital twin know-how have the potential to considerably enhance the analysis, therapy, and administration of sleep problems. AI can be utilized to investigate massive quantities of sleep knowledge, predict the chance of growing sleep problems, and make customized therapy suggestions. Digital twin know-how can be utilized to simulate entry to sufferers’ sleep patterns and analyze their sleep knowledge, which may also help to determine particular points and goal them extra successfully.

The mixing of those applied sciences with an built-in care group method can present a complete answer for sufferers with sleep problems, bettering the analysis, therapy, and administration of sleep problems, and finally bettering the standard of life for sufferers.

Using AI and digital twin know-how has an amazing potential to offer extra correct, environment friendly, and customized look after individuals affected by sleep problems, it could enhance entry to care and supply cost-effective options.



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